ErbB-2 Receptor

A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.

Also Known As:

Receptor, ErbB-2; Antigens, CD340; CD340 Antigen; Erb-b2 Receptor Tyrosine Kinases; Metastatic Lymph Node Gene 19 Protein; Neu Receptor; Oncogene Protein HER-2; Proto-Oncogene Proteins c-erbB-2; Proto-oncogene Protein Neu; Receptor, Neu; Receptors, erbB-2; Tyrosine Kinase-type Cell Surface Receptor HER2; p185(c-neu); p185erbB2 Protein; CD340 Antigens; Erb b2 Receptor Tyrosine Kinases; HER 2 Proto Oncogene Protein; Oncogene Protein HER 2; Proto Oncogene Protein HER 2; Proto Oncogene Proteins c erbB 2; Proto-Oncogene Protein, HER-2; Proto-Oncogene Protein, erbB-2; Proto-Oncogene Protein, neu; Tyrosine Kinase type Cell Surface Receptor HER2; c erbB 2 Protein; erbB 2 Proto Oncogene Protein; erbB 2 Receptor Protein Tyrosine Kinase; erbB-2 Receptors; neu Proto Oncogene Protein; HER-2 Proto-Oncogene Protein; Proto-Oncogene Protein HER-2; Proto-Oncogene Protein p185(neu); c-erbB-2 Protein; erbB-2 Proto-Oncogene Protein; erbB-2 Receptor Protein-Tyrosine Kinase; neu Proto-Oncogene Protein

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein-Tyrosine Kinases: 7827
        Receptor Protein-Tyrosine Kinases: 6127
        ErbB Receptors: 28658
        ErbB-2 Receptor: 526
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Membrane Proteins: 10262
    - Cell Surface Receptors: 2156
      - Receptor Protein-Tyrosine Kinases: 6127
        ErbB Receptors: 28658
        ErbB-2 Receptor: 526
      - Peptide Receptors: 1208
        Growth Factor Receptors: 2687
        ErbB Receptors: 28658
        ErbB-2 Receptor: 526
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7827
      - Receptor Protein-Tyrosine Kinases: 6127
        ErbB Receptors: 28658
        ErbB-2 Receptor: 526
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7896
      - Proto-Oncogene Proteins: 7
        ErbB-2 Receptor: 526
Biological Factors: 2560
- Biomarkers: 252800
  - Tumor Biomarkers: 15723
    - ErbB-2 Receptor: 526
- Antigens: 145631
  - Surface Antigens: 5857
    - Histocompatibility Antigens: 1126
      - Minor Histocompatibility Antigens: 394
        ErbB-2 Receptor: 526
  - Isoantigens: 1219
    - Histocompatibility Antigens: 1126
      - Minor Histocompatibility Antigens: 394
        ErbB-2 Receptor: 526

Arianna Cerretani Selected Research

Arianna Cerretani Research Topics

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